With the emergence of blockbuster drugs, such as Gazyva® (for Chronic Lymphocytic Leukemia) and POTELEGIO® (for Sézary syndrome), Fc engineered antibodies have garnered significant interest in the medical community, for various clinical conditions
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Roots Analysis has announced the addition of “Fc Protein and Glyco-engineered Antibodies Market2021-2030” report to its list of offerings.
Over time, a substantial body of evidence has validated the therapeutic applications of Fc engineering platforms; Fc modified antibodies have shown to augment the various immune effector functions, such as antibody-dependent cellular cytotoxicity (ADCC), complement-dependent cytotoxicity (CDC), antibody-dependent cellular phagocytosis (ADCP) activity and / or the half-life of the molecule
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Key Market Insights
The Fc engineered antibodies pipeline features more than 125 marketed drugs / drug development programs
Around 15% Fc protein and glyco-engineered antibodies are marketed, while close to 75% are being evaluated in different phases of clinical trials and 10% in preclinical studies. Examples of marketed Fc engineered antibodies include Gazvya®, Imfinzi®, MONJUVI® and Skyrizi®.
Around 30 companies claim to be engaged in the development of Fc protein and glyco-engineered antibodies
Around 55% of the aforementioned players are large companies (with more than 5000 employees). It is worth highlighting that, majority of the developers engaged in this domain (54%) are based in North America, followed by Europe (26%) and Asia-Pacific (20%).
Over 1,800 clinical trials are currently evaluating the therapeutic effects of Fc protein and glyco-engineered antibodies, worldwide
It is worth mentioning that most of the trials were / are being conducted in North America (35%) region;
however, more than 91% of the patients enrolled in trials conducted in North America were enrolled in different sites in the United States. Further, 43% of the trials are being sponsored by non-industry players.
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Key Questions Answered
- Who are the leading industry and non-industry players engaged in the development of Fc protein and glyco-engineered antibodies?
- Which are the key disease indications being targeted by Fc engineered antibodies?
- Which partnership models are commonly adopted by stakeholders engaged in this domain?
- Which geographies are the most active in conducting clinical trials on Fc protein and glyco-engineered antibodies?
- Which are the leading administering institutes supporting the research related to Fc protein and glyco-engineered antibodies?
- How has the intellectual property landscape in this market evolved over the years?
- Which key factors are likely to influence the evolution of this market?
- How is the current and future market opportunity likely to be distributed across key market segments?
For additional details, please visit
https://www.rootsanalysis.com/reports/fc-protein-engineered-and-glycoengineered-antibodies-market.html
or email sales@rootsanalysis.com
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