Enhancing Drug Safety and Efficacy Through Preclinical Testing | ZEFIT

ZEFIT is a biotech research company specializing in the development and discovery of new drugs using zebrafish models. Zefit utilizes advanced diagnostic technologies, including the Zebrafish Microinjection Automation System (Z-MAS™) and AI-driven ortholog prediction, to accelerate high-throughput preclinical drug discovery, with a focus on neurological disorders. Ultimately, Zefit’s services aim to improve efficiency, accuracy, and cost-effectiveness in drug screening and clinical trial success rate. 

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Models: 

• Zebrafish models are beneficial for screening therapeutic options, thanks to their highly conserved genes (80%~), which are crucial factors for successful drug development. 

• Zebrafish-based research favors identification of disease core targets and provides robust proof-of-concept data for preclinical research treatment strategies. 

• Zebrafish preclinical testing data has been utilised practically in drug R&D sector, drug R&D, saving global pharmaceutical companies over 10 million annually. In 2019, 2020, and 2021, FDA Investigational New Drug applications used zebrafish research data as the sole preclinical evidence, making it a viable alternative to traditional animal testing. 

• Advancements in zebrafish model techniques, including oral administration and intravenous injection, enhance precision and effectiveness in drug research, solidifying its role as a crucial preclinical model. 

Service: 

• The advanced neurological phenotyping and the use of the zebrafish as an ideal CNS model enable precise evaluation of neurological functions, efficient data collection, and Comprehensive research on Alzheimer’s disease (AD), Parkinson’s disease (PD), and epilepsy. Our CNS-FITTM models accurately mimics CNS disorders for compound screening and validation. 

Drug discovery: 

• Zefit is a team of experts working to streamline the early development process of disease treatment by utilizing a high-throughput drug development platform. Our innovative platform allows for the acquisition of non-clinical compounds within a year, reducing substantial time and cost of therapeutic research. 

If you are looking for a biopharmaceutical services, you can find them at ZEFIT. 

Click here if you have any further questions in ZEFIT services. 

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