BRCA1 and BRCA2 gene sequencing

BRCA 1 and BRCA 2 Genetic Testing to Screen for Risk of Breast Cancer

Prevention is better than cure and this truly applies to different forms of cancer like breast and ovarian cancer. The advanced BRCA mutation testing in India screens for the presence of BRCA1 and BRCA2 gene variations or mutation. Women with the gene variant for BRCA has 75% high chances of suffering from breast cancer or ovarian cancer.

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The BRCA1 and 2 screening is an ideal way to take the necessary preventive measures. With genetic counselling and powerful diagnostic, the identification of predisposition of cancer forming mutations helps in managing the associated risks.

The Cancer Genetic Testing Cost in India is affordable and screens for multiple gene mutation health risks. The positive result for BRCA testing help in taking necessary preventive steps before the occurrence of cancer.

BRCA Mutation – A Potential Carrier for Breast and Ovarian Cancer 

In a significant percentage of women, the underlying cause for cancer is the inheritance of the faulty gene. The mutation in either the BRCA1 and BRCA2 has high chances of forming either breast or ovarian cancer respectively. The BRCA genes are tumour suppressor genes that protect against cancer by repairing the DNA damage.

However, if there is any mutation, the genes might not be able to suppress cancer. BRCA gene test is highly recommended for women who have a family history of cancer or parents with an asymptomatic BRCA variant. The individuals with BRCA mutation are at higher risk of cancer due to the inability of the cell to repair DNA damage.

The breast cancer gene testing lab provides comprehensive pre and post-genetic counselling to help understand different aspects of the test. The screening process requires psychological counselling especially for the individuals who have tested positive for the mutation.

Risk of Cancer Development with the BRCA Mutation

Women detected with a BRCA1 mutation have nearly 60 – 70% of the risk of developing breast cancer in their lifetime. With BRCA2 mutation, the risk of developing cancer is 45 – 85%. The BRCA1 and BRCA2 Test costs in India are quite affordable as compared to the cost and expenses for the treatment of cancer. Screening does not reduce the risk of cancer but if tested positive, one can take the necessary preventive measures.

Screening for positive BRCA mutation can help with further prevention:

  • The next step recommended is breast screening through mammography and MRI which helps in the detection of breast cancer early on. It helps in getting necessary treatment before its onset into later stages.
  • Make changes in lifestyle and diet to reduce the risk of cancer. Healthy diet, physical exercise, and weight management help in reducing cancer risk.
  • Mastectomy is another preventive step which is a risk-reducing surgery with removal of the breast. The removal of ovaries is another preventive surgery for reducing the risk of ovarian cancer.

It is a breast cancer preventive test Delhi but does not 100% guarantee if there will be the onset of cancer or not. The test is a great way to seek further genetic counselling and take necessary steps to reduce the risk of cancer in near future.

Cost of Getting BRCA Test Cost India

The molecular diagnostic labs with genetic screening technology apply high throughput sequencing to analyze and screen for the presence of variants or mutations in the BRCA gene. The BRCA mutation testing cost varies between Rs 15000 to Rs 30000/- depending on the lab and its location. Most of the advanced labs help prepare an individual for the test through pre-genetic counselling discussing the process and further course of action. In case a person is tested positive, post genetic counselling help with personalized treatment and further diagnostic for preventive action.