Bleeding Disorders Treatment Market Highlights:
The bleeding disorder is a condition where the normal clotting function of blood is badly affected. In an injury, the blood normally starts to clot in order to prevent loss of blood. Occasionally, certain situations prevent blood from clotting properly, that can result in heavy or prolonged bleeding. Bleeding disorders can cause abnormal bleeding both outside and inside of the body. Some disorders can severely increase the amount of blood lost by the body.
Normal blood clotting involves blood components called ‘platelets’ and as many as there are 20 different plasma proteins in the body called as blood clotting or coagulation factors. These factors intermingle with other chemicals to form a substance called fibrin which stops bleeding. Complications can occur when certain factors are low or missing in the body. Bleeding problems can range from mild to severe. Some bleeding disorders are present at the time of birth and some are passed through families (inherited).
Growth in this market is credited to the rising R&D investments for the development and manufacturing of recombinant products by major players. The plasma-derived segment is projected to register the slowest CAGR, owed to its dropping demand from end users due to the threat of acquiring blood-associated infections. Moreover, difficulty in sourcing plasma from blood further confines the growth of plasma-derived coagulation factor concentrates market.
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Industry Segmentation
The global bleeding disorders treatment market has been segmented on the basis of type, drug class, treatment and end users.
On the basis of type, the market has been classified as hemophilia A, hemophilia B, Von Willebrand Disease (vWD) and others.
On the basis of drug class, the market has been classified as plasma-derived coagulation factor concentrates market, global recombinant coagulation factor concentrate market, global others bleeding disorders treatment market.
On the basis of treatment, the market has been classified as desmopressin (DDAVP), hormone replacement therapy, contraceptives, anti-fibrinolytic/clot-stabilizing drugs, fibrin sealants, drugs applied to cuts and pipeline analysis (phase I, phase II and phase III clinical trials)
On the basis of end users, the market has been classified as hospitals, clinics, specialty clinics, research institutes, and others.
Competitive Analysis by Major Key Players
Some of the key players in the global bleeding disorders treatment market are Shire Plc, Bayer Pharmaceuticals, Novo Nordisk A/S, Pfizer Inc., Biogen Idec, CSL Behring, Grifols, Octapharma, Sun Pharmaceutical Industries Ltd., BDI Pharma, Ferring Pharmaceuticals, and others.
Comprehensive Regional Analysis
The Americas is projected to lead the bleeding disorders treatment market in the forecast period. Increasing healthcare awareness, advancement in technology, medical tourism are some other factors that boost the growth of the market. According to the Centers for Disease Control and Prevention, Hemophilia A affects 1 in 5,000 male births and about 400 babies are born with hemophilia A each year.
The European market is expected to hold the second largest market share. The market is expected to witness growth owing to the rising patient population, changing lifestyle, and growing elderly population. This is expected to provide favorable backgrounds for the market to grow. According to annual report survey of 2015 by World Federation of Hemophilia, it is estimated that there were 523 million people suffering from hemophilia, 309 suffering from von Willebrand disease and 145 million people from bleeding disorders in Denmark.
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Asia-Pacific is projected to be the fastest growing region for the global bleeding disorders treatment in 2018. According to the annual report survey of 2015 by the World Federation of Hemophilia, it is estimated that there were 7,451 million people suffering from hemophilia and 1,950 suffering from von Willebrand disease in Russia. According to annual report survey of 2015 by World Federation of Hemophilia, it is estimated that there were 131 million people suffering from hemophilia, 2 suffering from von Willebrand disease and 7 million people from bleeding disorders in Hong Kong.
The Middle East and Africa accounts for the least share due to stringent government policies and low per capita income. According to annual report survey of 2015 by World Federation of Hemophilia, it is estimated that there were 2,206 million people suffering from hemophilia, 632 million people suffering from von Willebrand disease and 223 million people from bleeding disorders in South Africa